Protocol for KAT8 conditional knockout mice generation and its application in 4NQO-induced esophageal tumor model
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4-Nitroquinoline 1-oxide (4NQO), a quinoline derivative, induces tumor formation in mice following a multi-stage pattern analogous to human tumors, mimicking the natural carcinogenesis process. Here, we present a protocol for inducing esophageal squamous cell ... ...
