Solo regulates the localization and activity of LARG for actin cytoskeletal remodeling in cell-substrate adhesions
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In response to external mechanical stimuli, cells remodel their actin cytoskeleton. Solo, a Rho guanine nucleotide exchange factor (RhoGEF), is involved in mechanical stress responses via cell-substrate adhesions. Using BioID, we identified PDZ-RhoGEF (PRG), a... ...
