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Opioid Escalation in the ICU and 90-Day Readmission After Major Surgery: A Retrospective Cohort Study Using the MIMIC-IV Database

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BackgroundOpioid stewardship is central to postoperative critical care, yet the prognostic value of short-term opioid dose escalation in the intensive care unit (ICU) remains unclear. In non-ICU settings, escalating opioid requirements have been associated wit... ...