Natural triterpenoid glycosides, astragaloside II and astragaloside IV resensitize multidrug-resistant cancer via interfering ATPase activity and inducing apoptosis in vitro and in vivo
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Chemoresistance, often associated with multidrug resistance (MDR), is a significant challenge in cancer treatment. P-glycoprotein (P-gp) is overexpressed in various MDR cancers and is a drug efflux transporter of chemotherapeutics. Astragaloside II (AST-II) an... ...
