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Visible-Light-Driven Modular Synthesis of Isoquinolinone Derivatives via Palladium-Catalyzed Radical 6-endo Annulation of Aryl Halides

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Herein, a photoexcited-state palladium-catalyzed 6-endo selective annulation reaction of aryl-halide-tethered enamides has been developed, allowing various isoquinolinone motifs synthesized under mild conditions. This approach features operational simplicity, ... ...