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Resistance-exercise-induced stress intervenes in TGF-β signaling by cooperatively downregulating nuclear αB-crystallin and SMAD4 in human skeletal muscle fibers

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Alpha-crystallin B chain (αB-crystallin; CRYAB) helps to maintain proteostasis following cellular stress. Additionally, recent studies in fibroblasts have shown its function in the transforming growth factor beta (TGF-β) pathway, where it stabilizes mothers ... ...