A novel mechanism of selenium deficiency driving aberrant Th17 cell differentiation via GPX3-targeted PIG3: mitophagy blockade exacerbates mtDNA release
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Introduction: The biological functions of selenium (Se) are mainly realized through selenoproteins. As the only secreted antioxidant enzyme in the glutathione peroxidase family, the deficiency of glutathione peroxidase 3 (GPX3) c... ...