Synthesizing C8-Chiral Substituted 5,6,7,8-Tetrahydroquinolines via Palladium-Catalyzed Enantioselective Arylation of Unactivated C(sp3)-H Bonds
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Herein, we present a relatively green method for constructing C8-chiral substituted 5,6,7,8-tetrahydroquinoline (THQs) derivatives via palladium-catalyzed enantioselective arylation of unactivated C(sp3)-H bonds, using (S)-2-((tert-butoxycarbonyl)amino)-3,3-di... ...