Alendronate-conjugated liposome for targeting of osteoblastic prostate cancer: Evaluation of binding to bone matrix and in vivo targeting in a mouse model
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Prostate cancer bone metastases are predominantly osteoblastic, placing them in a unique position for bone-targeted drug delivery. Bone-targeted nanoparticles may be able to accumulate in aberrant bone formation inside these osteoblastic tumors, but this has n... ...
