Structure-activity landscape of Nurr1 (NR4A2) modulators: medicinal chemistry strategies for neurodegenerative disease intervention
{{output}}
Nuclear receptor-related 1 protein (Nurr1/NR4A2) is an orphan nuclear receptor essential for dopaminergic neuron development, maintenance, and survival. Nurr1 is highly expressed in the substantia nigra and regulates transcription of key dopaminergic genes, in... ...
