Direct β-C(sp3)-H Functionalization to Carbonyls: A Route to Aldehydic Acid Derivatives
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We describe a general strategy for C═O bond formation through palladium-catalyzed β-C(sp3)-H functionalization using sulfoximine as a neutral directing group. This method enables chemoselective oxidation of inert β-C(sp3)-H bonds to aldehydes with 2-nitro-i... ...
