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Coordinated translation initiation determines -1 programmed ribosomal frameshifting efficiency of chromosomal genes to impact on cell fitness

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The conserved -1 programmed ribosomal frameshifting (-1PRF), essential for eubacteria and RNA viruses, is thought to be exclusively regulated during translation elongation. One of the two required -1PRF cis-acting elements is a frameshifting stimulatory elemen... ...