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Dexmedetomidine suppresses ferritinophagy-mediated ferroptosis in myocardial ischemia-reperfusion injury via the YAP1/NCOA4 pathway

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The present study aimed to investigate the mechanism by which dexmedetomidine (Dex) mitigates myocardial ischemia-reperfusion injury (MIRI) through the regulation of ferritinophagy-mediated ferroptosis. In vivo, a rat MIRI model was established by surgical lig... ...