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Metabolic engineering of Escherichia coli for uridine-5'-diphosphate N-acetylglucosamine production through salvage pathway

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Uridine-5'-diphosphate N-acetylglucosamine (UDP-GlcNAc) has unique biological activities and is a key precursor for production of glycosaminoglycans and human milk oligosaccharides. Metabolic synthesis is considered as an economic strategy for UDP-GlcNAc prod... ...