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Determination of naloxone and its impurities in a vaporized matrix by LC-MS/MS: Application of an in vitro surrogate model platform to assess in vivo permeation and risk associated with vaping opioids

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E-cigarette use in the U.S. has risen over the past decade, particularly among youth and young adults, prompting potential public health concerns. In response, public health agencies including the FDA have initiated studies to assess associated risks from vapi... ...