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Discovery of 6,7-Dimethoxyquinazoline-Hydrazide Hybrids as Dual Inhibitors of Acetylcholinesterase and β-Secretase

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A novel series of 6,7-dimethoxyquinazoline-hydrazide hybrids 1-4 were designed, synthesized, and tested for their AChE inhibition activity using the qualitative assay, which showed that compounds 3 and 4 exhibited their activity via TLC. The compounds were cha... ...