Safety, pharmacokinetics, and preliminary efficacy of VS-01, an intraperitoneal liposomal infusion, in patients with decompensated liver cirrhosis, ascites, and covert hepatic encephalopathy: a phase 1b, first-in-human, open-label, non-randomised, single ascending and multiple dose study
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Background: Acute-on-chronic liver failure (ACLF) is characterised by systemic inflammation and organ failures in patients with decompensated liver cirrhosis. In the absence of specific approved treatments, ACLF is associated wit... ...
