Thermal Stability of IgG4 Monoclonal Antibodies: Ambiguous Roles of Cosolutes, Excipients, and Salts in Conformational and Colloidal States
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Peptide and antibody therapeutics are increasingly central to modern drug development, yet their formulation remains challenged by intrinsic instabilities and aggregation tendencies. In this work, we study the thermal stability of an IgG4 monoclonal antibody (... ...
