Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis
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METTL3, a key RNA N6-methyladenosine (m6A) methyltransferase, plays essential roles in cell fate regulation and tissue homeostasis, yet therapeutic strategies to enhance its activity remain unexplored. Here, we profile the S-palmitoylation landscape during emb... ...
