Novel cell-based assay enables FRET-based measurements of the dimerization activity of the chaperone DNAJB6
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The chaperone DNAJB6 inhibits aggregation of several amyloid proteins, such as α-synuclein and huntingtin, which are involved in neurodegenerative diseases. Here, we designed a cell-based assay to measure DNAJB6 dimerization in HEK293 cells by fluorescent res... ...
