Mechanical Dialogues of Life and Death: How External Molecules Entry Triggers a Chromatin-Cytoskeleton Morphogenetic Duel in Cancer Cells
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The next-generation anti-cancer therapeutics must disrupt intracellular mechanics, efficiently eradicating cancer cells, rather than simply intoxicating them. We evaluate the mechanism of action of PCMS, a PAMAM-based supramolecule that eradicates cancer cells... ...