Access to Hindered Homopropargylic Tertiary Alcohols via Nucleophilic Addition of Chiral Copper Species Forming an All-Carbon Quaternary Center
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We report the nucleophilic addition of chiral organocopper species derived from 1,3-enynes to carbonyl compounds, including ketones and aldehydes, providing efficient access to homopropargyl diols bearing an adjacent chiral all-carbon quaternary center. The re... ...
