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Disruption of the ∆40p53/miR-4671-5p/SGSH axis results in intra-S-phase arrest and poor cancer prognosis

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Parsing the functions of the tumor suppressor tumor protein p53 (TP53) is complex due to the multiple isoforms it encodes. ∆40p53, an N-terminally truncated p53 isoform and the only translational isoform, modulates full-length p53 (FLp53) activity and indepen... ...