Suppression of hepatic PPARα by hypoxia disrupts cholesterol metabolism and indirectly impairs arterial endothelial function in MASLD
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Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Currently, no approved targeted therapeutic interventions exist for MASLD. Hypoxia is known to exacerbate the pro... ...
