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Development and validation of a robust UPLC-MS/MS method for the analysis of polyamines in cells, biofluids and tissues

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Loss of function (LoF) of the ATP13A2 protein, a polyamines transporter, has been linked to lysosomal and mitochondrial dysfunctions that play an important role in the early onset of Parkinson's disease (PD) and related neurodegenerative disorders. To investi... ...