Copper-Catalyzed Synthesis of Medium-Sized Cyclic Aminals via Annulation of Ketenimines and N-Acyliminium Ions
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A CuBr-catalyzed intermolecular cascade strategy was developed to access medium-sized polycyclic aminals. While conventional cyclization encounters severe limitations due to inherent enthalpic and entropic constraints, this approach overcomes such challenges t... ...
