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Disease Modeling of Myocilin Mutation Dependent Normal Tension Glaucoma: Human Retinal Ganglion Cell Susceptibility to UPR and mTOR Signaling

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Glaucoma represents a group of diseases where the unifying theme is the progressive degeneration of retinal ganglion cells (RGC), causing irreversible vision loss. Mutations in the myocilin (MYOC) gene represent one of the most common genetic factors associate... ...