Hepatocyte-targeted Bap1 reduction in the liver primes an inflammatory transcriptional response
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BRCA1-associated protein 1 (BAP1) is a deubiquitinase, frequently altered in cancers including hepatocellular carcinoma and cholangiocarcinoma. While Bap1 has been shown to play key roles in metabolism, maintenance of tissue homeostasis, and immune cell develo... ...