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Protocol of ASPro-PD: a phase 3 trial of ambroxol to slow progression in genetically stratified Parkinson's disease

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Introduction: Genetic studies have identified the GBA1 gene as a significant genetic risk factor for Parkinson's disease (PD), with 10-15% of PD patients carrying GBA1 variants. GBA1 variants affect the glucocerebrosidase (GCase... ...