Plasma levels of thrombin-cleaved osteopontin as a surrogate biomarker of subsequent chronic shunt-dependent hydrocephalus development following aneurysmal subarachnoid hemorrhage
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Chronic shunt-dependent hydrocephalus (SDHC) is a major contributor to poor outcome after aneurysmal subarachnoid hemorrhage (aSAH), reportedly with arachnoid fibrosis implicated in its pathophysiology. In the pathogenesis of fibrosis, N-terminal half of osteo... ...