Preparation of novel in situ film-forming gel impregnated with clotrimazole-loaded liquid crystalline nanoparticles: In vitro, ex vivo, in vivo dermatopharmacokinetic and antifungal evaluation
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In an attempt to conquer the significant concerns, viz. patient discomfort due to repeated application, low skin permeability, retention, and low therapeutic efficacy of conventional topical formulations (creams, ointments, etc.) for the management of fungal i... ...