Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of 2-Pyrones with Acyclic Indolyl Alkenes for the Synthesis of Chiral N-Alkylindoles
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For the first time, this study employed a series of acyclic indolyl alkenes as dienophiles and successfully developed their inverse-electron-demand Diels-Alder (IEDDA) reactions with 2-pyrones, thereby constructing chiral N-alkylindole compounds bearing four c... ...
