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Phenotypic and functional heterogeneity of naïve CD8+ T cells in human peripheral blood during aging

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Naïve CD8+ T cells are key players of adaptive immunity, but their heterogeneity and age-related changes are not fully understood. This study aimed to compare naïve CD8+ T cell subsets defined by different combinations of markers, namely, NCCR7 (CD45RA+CCR7+... ...