Type I interferon-dependent and -independent signaling underlie autoantibody production in a murine lupus model
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Systemic lupus erythematosus (SLE) is characterized by the development of autoantibodies against diverse self-antigens and damage to multiple organs. Immunization with the SLE autoantigen β2-glycoprotein I and lipopolysaccharide (LPS) induces a murine model o... ...