Early serum S100β but not neuron-specific enolase reflects baseline CNS vulnerability in ICANS after CD19 CAR T-cell therapy
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Immune effector cell-associated neurotoxicity syndrome (ICANS) is a frequent complication of CD19 CAR T-cell therapy. Although several biomarkers, particularly S100β, have been reported to be associated with ICANS, their biological significance and specificit... ...