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Hirsutanines H-O, monoterpene indole alkaloids from Uncaria hirsuta with neuroprotective effects

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Hirsutanines H-O (1-8), eight previously undescribed monoterpene indole alkaloids, along with five known analogues (9-13), were isolated from the stems and leaves of Uncaria hirsuta. Compounds 1-4 represent a rare subclass of 3-oxo-3,7-seco-oxindole alkaloids.... ...