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ER-associated degradation pathway protein SEL1L plays an evolutionarily conserved role in platelet adhesion

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SEL1L is a well-known protein in the ER-associated degradation (ERAD) pathway. While it is known to be expressed in platelets, SEL1L has never been shown to play an active role. Here, we present evidence that SEL1L regulates platelet function. We first identif... ...