STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model
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Radiation therapy (RT) is the standard of care for glioblastoma but is not curative. Triggering the cGAS/stimulator of interferon genes (STING) pathway with potent agonists, such as 8803, exerts activity across high-grade glioma preclinical models. To determin... ...
