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Quantitative analysis of γ-H2AX foci kinetics: differential DNA damage response between primary PBMCs and HEp-2 tumor cells following gamma-irradiation

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The aims of this study was to establish a robust and quantitative methodological basis for the in vitro γ-H2AX assay, validating its dose-response and repair kinetics in both primary peripheral blood mononuclear cells (PBMCs) and human epithelial type 2 laryn... ...