Blood-brain barrier penetration determines link between beta blockers and reduced mortality in patients with sepsis-associated encephalopathy: A multicenter cohort study and an effect heterogeneity tool
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Clinical evidence for beta (β) blockers in sepsis-associated encephalopathy (SAE) is limited, and the influence of blood-brain barrier penetration (BBBp) on their neuroprotective efficacy remains unclear. We analyzed 17,446 SAE patients from the Medical Infor... ...
