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The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors

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The role of the Eph/ephrin system is well recognized in various physiological and pathological processes, including acute inflammation and cancer. We previously discovered that the secondary bile acid lithocholic acid (LCA) is a competitive antagonist of Eph r... ...