Efficient genetic perturbation of murine sensory neurons in vivo using CRISPR/Cas9
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Gene editing using CRISPR/Cas9 in vivo offers a powerful tool to investigate pain mechanisms. We generated a conditional knock-in mouse model where Streptococcus pyogenes CRISPR-associated protein 9 (Cas9) expression is restricted to cells that express SCN9A. ... ...
