The RRM domains of PARP14 mediate replication fork degradation in BRCA2-deficient cells
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Degradation of reversed replication forks by nucleases has emerged as a major mechanism of chemosensitivity in BRCA-deficient cells. We previously showed that the mono-ADP-ribosyltransferase PARP14 regulates MRE11 recruitment to reversed replication forks to p... ...
