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Synthesis of Tetralin and Chromane Motifs via Pd-Catalyzed Dual C(sp3)-H/C(sp2)-H Bond Activation

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A palladium-catalyzed intramolecular selective dual C-H bond activation between aliphatic β-C(sp3)-H and aromatic C(sp2)-H bonds of substituted sulfonamides is described. This methodology is highly compatible for building up privileged chromane and tetralin s... ...