Genetic variants of flavin-containing monooxygenase (FMO) 1 and FMO3 in 5887 dogs influenced oxygenations of probe substrates benzydamine, trimethylamine, and methyl p-tolyl sulfide
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NADPH-dependent flavin-containing monooxygenases (FMOs; EC 1.14.13.8) mediate the oxygenation of various N- or S-containing molecules. Human FMO1 and FMO3 metabolize the substrates benzydamine, trimethylamine, and methyl p-tolyl sulfide in the kidney and liver... ...
