SNAP25 undergoes phase separation to facilitate the assembly of the synaptic vesicle fusion machinery
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The assembly of the SNARE complexes drives synaptic exocytosis in neurotransmission. SNAP25 is a key SNARE protein that pairs with syntaxin-1 and VAMP2 in synaptic vesicle fusion. The dysfunction of SNAP25 is associated with neurodevelopmental and neurodegener... ...