BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD
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Autosomal-dominant polycystic kidney disease (ADPKD) is primarily of adult-onset and caused by pathogenic variants in PKD1 or PKD2. Yet, disease expression is highly variable and includes very early-onset PKD presentations in utero or infancy. In animal models... ...
