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Beyond Conventional Transcriptional Regulation Function: FOXP3 as an Integrative Hub for Chromatin Interactions and Protein Complexes in Immune Regulation

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As the lineage-defining transcription factor for regulatory T cells (Tregs), FOXP3 plays a critical role in maintaining immune homeostasis. However, FOXP3 has not been found to regulate the expression of immune suppressive cytokines so far, and the specific mo... ...