Cu-Catalyzed Cross-Coupling Reactions of Enamines and Terminal Alkynes: Access of Propargylamines as Neurodegenerative Disorder Agents
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Reactions between enamine analogues and terminal alkynes were explored. Copper(I) complex of 1,10-phenanthroline catalyzed these reactions to generate a diastereoselective propargylamines via C-C bond formation. In the presence of Zn2+, the chiral propargylami... ...