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DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase

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Various methods have been developed for 5-methylcytosine (5mC) sequencing; however, effective ways to enrich hypomethylated DNA regions have been limited. Here, we describe the DEMETER-assisted 5-Methylcytosine Nicking sequencing (DMN-seq) utilizing 5mC-specif... ...